Force-velocity relation for growing biopolymers
نویسندگان
چکیده
منابع مشابه
Force-velocity relation for growing microtubules.
Forces generated by microtubule polymerization and depolymerization are important for the biological functioning of cells. The mean growth velocity, V, under an opposing force, F, has been measured by; Science 278:856-860) for single microtubules growing in vitro, but their analysis of the data suggested that V decreased more rapidly with F than equilibrium (or "thermodynamic") theory predicted...
متن کاملMeasurement of the force-velocity relation for growing microtubules.
Forces generated by protein polymerization are important for various forms of cellular motility. Assembling microtubules, for instance, are believed to exert pushing forces on chromosomes during mitosis. The force that a single microtubule can generate was measured by attaching microtubules to a substrate at one end and causing them to push against a microfabricated rigid barrier at the other e...
متن کاملMeasurement of the Force - Velocity Relation for Growing Microtubules
8. S.-J. Lin, R. A. Pufahl, A. Dancis, T. V. O’Halloran, V. Cizewski Culotta, J. Biol. Chem. 272, 9214 (1997). 9. L. W. J. Klomp et al., ibid., p. 9221. 10. C. Vulpe et al., Nature Genet. 3, 7 (1993). 11. P. C. Bull et al., ibid. 5, 327 (1993); R. E. Tanzi et al., ibid., p. 344. 12. S. Lutsenko and J. H. Kaplan, Biochemistry 34, 15607 (1995). 13. M. J. Petris et al., EMBO J. 15, 6084 (1996). 14...
متن کاملMeasurement of the Force - Velocity Relation for
www.sciencemag.org (this information is current as of February 4, 2008 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/278/5339/856 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/278/5339/856#otherarticles ,...
متن کاملForce-Velocity Measurements of a Few Growing Actin Filaments
The polymerization of actin in filaments generates forces that play a pivotal role in many cellular processes. We introduce a novel technique to determine the force-velocity relation when a few independent anchored filaments grow between magnetic colloidal particles. When a magnetic field is applied, the colloidal particles assemble into chains under controlled loading or spacing. As the filame...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Physical Review E
سال: 2000
ISSN: 1063-651X,1095-3787
DOI: 10.1103/physreve.62.7082